Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.57 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 1/20 | 0.46 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360246 | 0.89 | ERN1 (0.59) | ERN1TRIM24TYRTRIM33 | |
| SCHEMBL30066894 | 0.89 | ERN1 (0.59) | ERN1TRIM24TYRTRIM33 | |
| SCHEMBL5227187 | 0.81 | MTNR1A (0.59) | ERN1MTNR1AMTNR1BALDH1A1GAA | |
| SCHEMBL19305505 | 0.80 | ERN1 (0.53) | ERN1TRIM24TRIM33ALDH1A1GAA | |
| SCHEMBL16800507 | 0.78 | MTNR1A (0.43) | ERN1TRIM24TYRTRIM33MTNR1A | |
| SCHEMBL18156885 | 0.77 | ERN1 (0.59) | ERN1 | |
| SCHEMBL12674873 | 0.77 | ERN1 (0.47) | ERN1 | |
| SCHEMBL12674913 | 0.77 | PTPN7 (0.53) | ERN1MTNR1AALDH1A1LMNA | |
| SCHEMBL29218980 | 0.77 | MEN1 (0.50) | ERN1TRIM24TYRTRIM33MTNR1A | |
| SCHEMBL3906221 | 0.77 | ERN1 (0.63) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115813893-B | Application of naphthyl skeleton compound in preparation of coronavirus 3CL protease inhibitor | 陕西科技大学 | 2025-01-28 | — | — | CN | claimed |
| CN-115813893-A | Application of naphthyl skeleton compound in preparing coronavirus 3CL protease inhibitor | 陕西科技大学 | 2023-03-21 | — | — | CN | claimed |
| CN-119661399-A | Synthesis and antibacterial application of novel Schiff base gold (III) compounds | 南京中医药大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-115813893-B | Application of naphthyl skeleton compound in preparation of coronavirus 3CL protease inhibitor | 陕西科技大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-115813893-A | Application of naphthyl skeleton compound in preparing coronavirus 3CL protease inhibitor | 陕西科技大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-105566276-B | Benzo-hexatomic ring derivative as DPP-4 inhibitor and application thereof | 华东理工大学 | 2021-01-08 | — | — | CN | disclosed |
| EP-3214079-B1 | SIX-MEMBERED RING BENZO DERIVATIVES AS DPP-4 INHIBITOR AND USE THEREOF | UNIV EAST CHINA SCIENCE & TECH (CN) | 2020-06-24 | — | — | EP | disclosed |
| EP-3214079-B1 | SIX-MEMBERED RING BENZO DERIVATIVES AS DPP-4 INHIBITOR AND USE THEREOF | UNIV EAST CHINA SCIENCE & TECH (CN) | 2020-06-24 | — | — | EP | disclosed |
| US-10479798-B2 | Six-membered ring benzo derivatives as DPP-4 inhibitor and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-11-19 | — | — | US | disclosed |
| US-10479798-B2 | Six-membered ring benzo derivatives as DPP-4 inhibitor and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-11-19 | — | — | US | disclosed |
| CN-110372663-A | Sulfur heterocyclic compound and its application as DPP4 inhibitor derivates | 山东百极地长制药有限公司 | 2019-10-25 | — | — | CN | disclosed |
| US-20160304429-A1 | PROCESS FOR THE SYNTHESIS OF 7-METHOXY-NAPHTHALENE-1-CARBALDEHYDE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE | LES LABORATOIRES SERVIER (FR) | 2016-10-20 | — | — | US | disclosed |
| CN-105793226-A | Novel method for the synthesis of 7-methoxy-naphthalene-1-carbaldehyde and use thereof in the synthesis of agomelatine | 法国施维雅药厂 | 2016-07-20 | — | — | CN | disclosed |
| EP-0998471-B1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-03-14 | — | — | EP | disclosed |
| US-6602903-B2 | Substituted O- and/or S heterocyclic compounds; powerful ligands for melatoninergic receptors. | LES LABORATORIES SERVIER (FR) | 2003-08-05 | — | — | US | disclosed |
| US-20020052400-A1 | Substituted heterocyclic compounds | ADIR ET COMPAGNIE | 2002-05-02 | — | — | US | disclosed |
| US-6313160-B1 | FOR THERAPY AND PROPHYLAXIS OF MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0998471-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 2000-05-10 | — | — | EP | disclosed |
| WO-1998052935-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1998-11-26 | — | — | WO | disclosed |
| US-4341794-A | ANIMAL GROWTH REGULATOR | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (FR) | 1982-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304429-A1 | PROCESS FOR THE SYNTHESIS OF 7-METHOXY-NAPHTHALENE-1-CARBALDEHYDE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE | COMT, TPH1, TPH2 | ERN1 2609/4885TRIM24 2216/4885TYR 9/4885 |
| US-10479798-B2 | Six-membered ring benzo derivatives as DPP-4 inhibitor and use thereof | DPP4, DPP7, DPP3 | ERN1 3887/4885TRIM24 2106/4885TYR 802/4885 |
| US-20020052400-A1 | Substituted heterocyclic compounds | MTNR1A, MTNR1B, CBR1 | ERN1 3046/4885TRIM24 3487/4885TYR 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.