Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716570 | 0.83 | TSHR (0.42) | KIF11TSHRGLAPOLBGAA | |
| SCHEMBL2570700 | 0.83 | KIF11 (0.47) | KIF11TSHRGLAPOLBGAA | |
| SCHEMBL18999755 | 0.82 | KIF11 (0.44) | KIF11TSHRGLAPOLBGAA | |
| SCHEMBL31481037 | 0.81 | KIF11 (0.50) | KIF11TSHRGLAPOLBGAA | |
| SCHEMBL12982710 | 0.79 | KIF11 (0.41) | KIF11TSHRGLAPOLBGAA | |
| SCHEMBL1507033 | 0.78 | KCNN4 (0.43) | GAAALDH1A1LMNAKCNN4 | |
| SCHEMBL29727285 | 0.78 | KCNN4 (0.43) | GAAALDH1A1LMNAKCNN4 | |
| SCHEMBL13858152 | 0.78 | KIF11 (0.47) | KIF11TSHRGLAPOLBGAA | |
| SCHEMBL28402360 | 0.78 | TSHR (0.55) | KIF11TSHRGLAPOLBGAA | |
| SCHEMBL30619303 | 0.78 | TSHR (0.55) | KIF11TSHRGLAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| US-10011566-B2 | Compounds | ASTRAZENECA AB (SE) | 2018-07-03 | — | — | US | disclosed |
| US-9738600-B2 | ROR gamma (RORγ) modulators | LEAD PHARMA CEL MODELS IP B.V. (NL) | 2017-08-22 | — | — | US | disclosed |
| US-20170166527-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2017-06-15 | — | — | US | disclosed |
| US-20160304448-A1 | ROR GAMMA (RORy) MODULATORS | LEAD PHARMA CEL MODELS IP B.V. (NL) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011566-B2 | Compounds | RORC, RORB, RORA | KIF11 2375/4885TSHR 953/4885GLA 2175/4885 |
| US-20160304448-A1 | ROR GAMMA (RORy) MODULATORS | RORC, RORA, RORB | KIF11 570/4885TSHR 167/4885GLA 3523/4885 |
| US-20170166527-A1 | Novel Compounds | RORC, RORB, RORA | KIF11 2594/4885TSHR 1099/4885GLA 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.