Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | RORC | P51449 | 12/20 | 0.60 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.58 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.58 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.58 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.54 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18151409 | 0.90 | RORC (0.75) | ALDH1A1RORCABCC9ABCC8KCNJ11 | |
| SCHEMBL18156899 | 0.87 | RORC (0.64) | RORC | |
| SCHEMBL18156909 | 0.87 | KCNJ6 (0.53) | ALDH1A1RORCABCC9ABCC8KCNJ11 | |
| SCHEMBL17114491 | 0.86 | RORC (0.80) | RORC | |
| SCHEMBL18156902 | 0.84 | RORC (0.60) | RORC | |
| SCHEMBL18156903 | 0.83 | RORC (0.69) | RORC | |
| SCHEMBL18156918 | 0.82 | RORC (0.64) | RORC | |
| SCHEMBL16799539 | 0.81 | RORC (0.63) | RORC | |
| SCHEMBL18151510 | 0.81 | RORC (0.56) | RORCMAPT | |
| SCHEMBL18151624 | 0.77 | RORC (0.60) | ALDH1A1RORCABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738600-B2 | ROR gamma (RORγ) modulators | LEAD PHARMA CEL MODELS IP B.V. (NL) | 2017-08-22 | — | — | US | disclosed |
| US-20160304448-A1 | ROR GAMMA (RORy) MODULATORS | LEAD PHARMA CEL MODELS IP B.V. (NL) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304448-A1 | ROR GAMMA (RORy) MODULATORS | RORC, RORA, RORB | ALDH1A1 1054/4885RORC 1/4885ABCC9 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.