SCHEMBL18157767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1029936	0.80	MAPT (0.44)	APPCYP19A1ALDH1A1GPR3HSD17B10
	SCHEMBL4892717	0.80	CYP19A1 (0.64)	APPCYP19A1ALDH1A1GPR3HSD17B10
	Diphenylacetylene SCHEMBL6544119	0.80	ALDH1A1 (0.67)	APPCYP19A1ALDH1A1GPR3HSD17B10
	SCHEMBL5635075	0.76	AHR (0.41)	APPALDH1A1GPR3HSD17B10ATM
	SCHEMBL18157757	0.74	NPC1 (0.43)	APPALDH1A1GPR3HSD17B10ATM
	SCHEMBL18157760	0.74	NPC1 (0.40)	APPCYP19A1ALDH1A1GPR3HSD17B10
	SCHEMBL29357652	0.73	APP (0.67)	APPALDH1A1HSD17B10ATMKDM4E
	SCHEMBL55761	0.73	APP (0.67)	APPALDH1A1HSD17B10ATMKDM4E
	SCHEMBL29316737	0.71	ALDH1A1 (0.39)	CYP19A1ALDH1A1GPR3HSD17B10ATM
	SCHEMBL3796509	0.70	APP (0.80)	APPALDH1A1HSD17B10KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.