SCHEMBL18157760

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18157757	0.76	NPC1 (0.43)	NPC1RAB9AMEN1KMT2AMAPT
	Diphenylacetylene SCHEMBL15666790	0.74	APP (0.67)	MEN1KMT2AMAPTFFAR1CYP19A1
	SCHEMBL28555372	0.74	NPC1 (0.50)	NPC1RAB9AMEN1KMT2AMAPT
	SCHEMBL18157755	0.74	NPC1 (0.50)	NPC1RAB9AMEN1KMT2AMAPT
	SCHEMBL18157767	0.74	APP (0.44)	MEN1KMT2AMAPTKDM4EGLA
	SCHEMBL4892717	0.72	CYP19A1 (0.64)	MEN1KMT2AMAPTKDM4ENPSR1
	(Z)-1,2-Diphenylethene SCHEMBL4393598	0.72	ALDH1A1 (0.67)	NPC1RAB9AMEN1KMT2AMAPT
	Diphenylacetylene SCHEMBL6544119	0.72	ALDH1A1 (0.67)	MEN1KMT2AMAPTKDM4EGLA
	(Z)-1,2-Diphenylethene SCHEMBL4393600	0.72	ALDH1A1 (0.67)	NPC1RAB9AMEN1KMT2AMAPT
	SCHEMBL18160163	0.71	ESR1 (0.55)	NPC1RAB9AMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.