Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 20/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 20/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | HTR1D | P28221 | 1/20 | 0.62 |
| ▸ | HTR1B | P28222 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926323 | 0.96 | ADRA1A (0.64) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL524564 | 0.96 | ADRA1A (0.64) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL13729913 | 0.96 | ADRA1A (0.64) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Oxalic Acid SCHEMBL28644138 | 0.95 | ADRA1A (0.62) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Oxalic Acid SCHEMBL28644141 | 0.95 | ADRA1A (0.62) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Oxalic Acid SCHEMBL526172 | 0.95 | ADRA1A (0.62) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL28996811 | 0.91 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Alpha-Ketoglutaric Acid SCHEMBL17026691 | 0.91 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL13037438 | 0.89 | ADRA1A (0.59) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL16422055 | 0.88 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745264-B2 | Method for preparing silodosin and intermediate thereof | SHANGHAI SYNCORES TECHNOLOGIES, INC. (CN) | 2017-08-29 | — | — | US | disclosed |
| US-20160304452-A1 | METHOD FOR PREPARING SILODOSIN AND INTERMEDIATE THEREOF | ZHEJIANG HUAHAI PHARMACEUTICALS CO., LTD. (CN) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304452-A1 | METHOD FOR PREPARING SILODOSIN AND INTERMEDIATE THEREOF | PTMA, PIR, ERG28 | ADRA1D 219/4885ADRA1A 396/4885ADRA1B 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.