SCHEMBL18158124

SCHEMBL18158124

O=C(NS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.54
PTGS1 P23219 2/20 0.52
TLR7 Q9NYK1 3/20 0.47
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
LMNA P02545 1/20 0.43
METAP2 P50579 1/20 0.43
METAP1 P53582 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GRM4 Q14833 3/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43
MEN1 O00255 1/20 0.43
PSMD14 O00487 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17490970 0.84 PTGS2 (0.60) PTGS2PTGS1TLR7NPC1RAB9A
SCHEMBL17853372 0.78 P2RX7 (0.49) PTGS2PTGS1
SCHEMBL2735009 0.74 PTGS2 (0.53) PTGS2PTGS1NPC1RAB9ASMN1; SMN2
SCHEMBL18717784 0.73 PTGS1 (0.36) PTGS2PTGS1
SCHEMBL29029414 0.72 PTGS2 (0.66) PTGS2PTGS1NPC1RAB9ASMN1; SMN2
SCHEMBL1570558 0.71 TLR7 (0.58) PTGS2TLR7NPC1RAB9ASMN1; SMN2
SCHEMBL18157894 0.70 PTGS2 (0.71) PTGS2PTGS1TLR7NPC1RAB9A
SCHEMBL30430782 0.70 PTGS2 (1.00) PTGS2PTGS1NPC1RAB9ASMN1; SMN2
SCHEMBL7226092 0.70 PTGS2 (1.00) PTGS2PTGS1NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL26929400 0.69 TLR7 (0.56) PTGS2TLR7NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 PTGS2 4041/4885PTGS1 3758/4885TLR7 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.