SCHEMBL18158403

SCHEMBL18158403

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nc(-c5ccccc5)c5sc6ccccc6c5n4)cc3)n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ ATM Q13315 1/20 0.48
▸ TNKS O95271 2/20 0.42
▸ TNKS2 Q9H2K2 2/20 0.42
▸ ALDH1A1 P00352 4/20 0.39
▸ LIMK1 P53667 3/20 0.39
▸ GAA P10253 2/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ CYP2D6 P10635 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CDK5 Q00535 1/20 0.39
▸ CDK5R1 Q15078 1/20 0.39
▸ PIK3CA P42336 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ MAPT P10636 4/20 0.37
▸ PIM1 P11309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19106305 1.00 MEN1 (0.48) MEN1KMT2AATMTNKSTNKS2
SCHEMBL19106198 0.98 MEN1 (0.47) MEN1KMT2AATMTNKSTNKS2
SCHEMBL18158405 0.98 MEN1 (0.47) MEN1KMT2AATMTNKSTNKS2
SCHEMBL19106267 0.98 MEN1 (0.47) MEN1KMT2AATMTNKSTNKS2
SCHEMBL18158406 0.98 MEN1 (0.47) MEN1KMT2AATMTNKSTNKS2
SCHEMBL18158408 0.98 MEN1 (0.47) MEN1KMT2AATMTNKSTNKS2
SCHEMBL19106306 0.98 MEN1 (0.47) MEN1KMT2AATMTNKSTNKS2
SCHEMBL19106195 0.98 MEN1 (0.47) MEN1KMT2AATMTNKSTNKS2
SCHEMBL18017848 0.98 MEN1 (0.45) MEN1KMT2AATMTNKSTNKS2
SCHEMBL18017854 0.98 MEN1 (0.45) MEN1KMT2AATMTNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10734588-B2 Compound for organic electronic element, and organic electronic element and electronic device using same DUK SAN NEOLUX CO., LTD (KR) 2020-08-04 — — US disclosed
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2019-06-11 — — US disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 — — US disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 — — US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 — — US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 — — US disclosed
US-20170200903-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ORGANIC ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME DUK SAN NEOLUX CO., LTD. (KR) 2017-07-13 — — US disclosed
US-20170200903-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ORGANIC ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME DUK SAN NEOLUX CO., LTD. (KR) 2017-07-13 — — US disclosed
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 — — US disclosed
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MEN1 838/4885KMT2A 2013/4885ATM 1355/4885
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device OR10J3, OR51E2, OXER1 MEN1 2391/4885KMT2A 4764/4885ATM 4359/4885
US-20170200903-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ORGANIC ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME NFE2L2, ESR1, VDAC2 MEN1 1003/4885KMT2A 581/4885ATM 2511/4885
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE OCIAD2, OCIAD1, OR10J3 MEN1 2593/4885KMT2A 3837/4885ATM 4302/4885
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 MEN1 2498/4885KMT2A 4763/4885ATM 4365/4885
US-10734588-B2 Compound for organic electronic element, and organic electronic element and electronic device using same NFE2L2, ESR1, VDAC2 MEN1 1003/4885KMT2A 581/4885ATM 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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