Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397150 | 0.84 | SMN1; SMN2 (0.48) | VCAM1SMN1; SMN2XDHALDH5A1ABAT | |
| SCHEMBL29859149 | 0.84 | SMN1; SMN2 (0.48) | VCAM1SMN1; SMN2XDHALDH5A1ABAT | |
| SCHEMBL4175079 | 0.78 | VCAM1 (0.54) | VCAM1SMN1; SMN2XDHALDH5A1ABAT | |
| SCHEMBL29956980 | 0.75 | XDH (0.54) | VCAM1XDHALDH5A1ABATALDH3A1 | |
| SCHEMBL27823778 | 0.75 | XDH (0.46) | VCAM1SMN1; SMN2XDHALDH5A1ABAT | |
| SCHEMBL29951203 | 0.75 | XDH (0.46) | VCAM1SMN1; SMN2XDHALDH5A1ABAT | |
| SCHEMBL14060039 | 0.71 | ALDH1A1 (0.45) | VCAM1SMN1; SMN2XDHALDH5A1ABAT | |
| SCHEMBL10951439 | 0.67 | VCAM1 (0.63) | VCAM1XDHALDH5A1ABATALDH3A1 | |
| SCHEMBL6538062 | 0.67 | PDE10A (0.57) | VCAM1SMN1; SMN2ALDH5A1ABATALDH1A1 | |
| SCHEMBL795882 | 0.66 | MEN1 (0.62) | SMN1; SMN2ALDH1A1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | VIP, MRPL21, THEM6 | VCAM1 2457/4885SMN1; SMN2 4755/4885XDH 3306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.