SCHEMBL1815922

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16383670	0.88	KDM4E (1.00)	KDM4EMEN1KMT2AKCNK3KCNK9
	SCHEMBL15775402	0.86	KDM4E (0.77)	KDM4EMEN1KMT2AS1PR4KCNK3
	SCHEMBL9523014	0.85	S1PR4 (0.69)	KDM4EKMT2AS1PR4SMN1; SMN2NPC1
	SCHEMBL9522743	0.84	S1PR4 (0.58)	KDM4EMEN1KMT2AS1PR4NPC1
	SCHEMBL4138460	0.83	POLB (0.67)	KDM4EMEN1KMT2AS1PR4KCNK3
	SCHEMBL9525322	0.83	NPC1 (0.59)	KDM4EMEN1KMT2AS1PR4LMNA
	SCHEMBL11123393	0.82	RXFP1 (0.59)	KDM4EMEN1KMT2AS1PR4KCNK3
	SCHEMBL9522953	0.82	S1PR4 (0.56)	KDM4EMEN1KMT2AS1PR4SMN1; SMN2
	Ameltolide SCHEMBL635392	0.82	S1PR4 (0.56)	KDM4EMEN1KMT2AS1PR4LMNA
	SCHEMBL2307872	0.82	S1PR4 (0.56)	KDM4EMEN1KMT2AS1PR4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.