Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806823 | 0.69 | LIPA (0.45) | LIPAKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL19584750 | 0.69 | LIPA (0.49) | LIPAKMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL8957690 | 0.68 | — | — | |
| SCHEMBL13116718 | 0.68 | USP2 (0.55) | LIPAALDH1A1KDM4EMAPTCASP1 | |
| SCHEMBL8804737 | 0.67 | LIPA (0.42) | LIPAKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL13116719 | 0.65 | HRH1 (0.54) | LIPAALDH1A1KDM4EMAPTCASP1 | |
| SCHEMBL329990 | 0.63 | MEN1 (0.35) | KMT2AMEN1TSHR | |
| SCHEMBL10242357 | 0.63 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL330360 | 0.62 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL12252421 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160303133-A1 | TREATMENT OF GASTROINTESTINAL AND OTHER DISORDERS | NUMEDII, INC. (US) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160303133-A1 | TREATMENT OF GASTROINTESTINAL AND OTHER DISORDERS | ADRB1, ADRB2, ADRA2B | LIPA 957/4885KMT2A 4617/4885MEN1 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.