Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19552247 | 0.87 | VCAM1 (0.57) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL19071888 | 0.84 | VCAM1 (0.57) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL18545709 | 0.82 | VCAM1 (0.58) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL2543816 | 0.81 | VCAM1 (0.54) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3860770 | 0.81 | VCAM1 (0.54) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL2539773 | 0.80 | VCAM1 (0.53) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL73860 | 0.77 | VCAM1 (0.70) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL20380048 | 0.77 | VCAM1 (0.49) | VCAM1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL1817485 | 0.76 | HSD17B10 (0.60) | VCAM1ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL17259 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478188-A | Fluorescent probe and preparation method and application thereof | 澳门大学 | 2023-07-25 | — | — | CN | claimed |
| CN-116478188-A | Fluorescent probe and preparation method and application thereof | 澳门大学 | 2023-07-25 | — | — | CN | disclosed |
| US-8709721-B2 | Fluorescent molecule and method for detecting target nucleic acid | RIKEN (JP) | 2014-04-29 | — | — | US | disclosed |
| US-8461134-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| EP-2484671-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | Riken (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120196377-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | RIKEN (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20110172187-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| WO-2011060196-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172187-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, BTD | VCAM1 1484/4885ALDH1A1 4190/4885LMNA 3490/4885 |
| US-20120196377-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | DNTT, POLL, POLRMT | VCAM1 3028/4885ALDH1A1 462/4885LMNA 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.