SCHEMBL1816352

SCHEMBL1816352

Clc1nnnc(-c2ccccc2)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 3/20 0.49
HTT P42858 3/20 0.48
KDM4E B2RXH2 4/20 0.45
PKM P14618 1/20 0.45
ALDH1A1 P00352 1/20 0.42
GLA P06280 1/20 0.42
HPGD P15428 1/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALOX15 P16050 1/20 0.38
MAPK1 P28482 2/20 0.37
XDH P47989 1/20 0.37
KMT2A Q03164 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
ADORA2A P29274 2/20 0.36
ADORA1 P30542 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28212978 0.89 LMNA (0.54) LMNASMN1; SMN2MAPTHTTKDM4E
SCHEMBL1898825 0.81 LMNA (0.47) LMNASMN1; SMN2MAPTHTTKDM4E
SCHEMBL9138181 0.80 KDM4E (0.47) LMNASMN1; SMN2MAPTKDM4EPKM
SCHEMBL7197255 0.73 LMNA (0.56) LMNASMN1; SMN2MAPTHTTKDM4E
SCHEMBL28152930 0.72 LMNA (0.41) LMNASMN1; SMN2MAPTHTTKDM4E
SCHEMBL28576050 0.72 KDM4E (0.44) LMNASMN1; SMN2KDM4EPKMALDH1A1
SCHEMBL500715 0.72 LMNA (0.56) LMNASMN1; SMN2MAPTHTTKDM4E
Toluene SCHEMBL1726243 0.71 LMNA (0.50) LMNASMN1; SMN2MAPTKDM4EALDH1A1
SCHEMBL9137373 0.71 KDM4E (0.42) LMNASMN1; SMN2MAPTKDM4EPKM
SCHEMBL22360955 0.70 LMNA (0.54) LMNASMN1; SMN2MAPTHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60260503-A None JP disclosed
CN-110520504-B Composition for phosphorescent host, organic optoelectronic device and display device 三星SDI株式会社 2023-12-01 CN disclosed
CN-111808082-B Luminescent material and application thereof 北京鼎材科技有限公司 2023-10-17 CN disclosed
CN-112028879-B Electron transport material, organic electroluminescent device and display device 烟台京师材料基因组工程研究院 2023-07-21 CN disclosed
US-20210111350-A1 PHOSPHORESCENT HOST COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-04-15 US disclosed
US-20200168819-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-28 US disclosed
CN-110364632-A Composition and organic photoelectric device and display device 三星SDI株式会社 2019-10-22 CN disclosed
US-9761811-B2 Organic electroluminescence element and material for organic electroluminescence element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2017-09-12 US disclosed
EP-2869356-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2016-10-12 EP disclosed
US-20150249217-A1 TRIAZINE-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-09-03 US disclosed
WO-2011054442-A2 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-05-12 WO disclosed
CN-1137106-C Process for preparation of phenyldichloro-1,3,5-triazine compounds �������⻯ѧƷ�ع����޹�˾ 2004-02-04 CN disclosed
US-6057444-A REACTION OF ALDEHYDE WITH BIURET IN HYDROCHLORIC ACID WITH METHYLSULFONIC ACID, OXIDATION AND CHLORINATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US disclosed
CN-1228426-A Process for preparation of phenyldichloro-1,3,5-triazine compounds CIBA SC HOLDING AG (CH) 1999-09-15 CN disclosed
JP-S60260503-A METHOD OF REDUCING CHEMICAL INJURY OF HERBICIDE AND COMPOSITION THEREFOR NISSAN CHEM IND LTD 1985-12-23 JP disclosed
EP-0057382-B1 PROCESS FOR THE PREPARATION OF VAT DYES FROM THE WASTE PRODUCTS OF THE SYNTHESIS OF NITRO-ANTHRAQUINONE AND ANTHRAQUINONE SULFONIC ACID BAYER AG (DE) 1983-12-28 EP disclosed
EP-0057382-A2 Process for the preparation of vat dyes from the waste products of the synthesis of nitro-anthraquinone and anthraquinone sulfonic acid BAYER AG (DE) 1982-08-11 EP disclosed
EP-0017768-B1 REACTIVE DYESTUFFS AND THEIR USE BASF Aktiengesellschaft (DE) 1981-11-25 EP disclosed
EP-0017768-A1 Reactive dyestuffs and their use BASF Aktiengesellschaft (DE) 1980-10-29 EP disclosed
US-4198205-A SULFONIC ACID-FREE DISPERSE DYES BASF AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150249217-A1 TRIAZINE-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME IKZF2, POU5F1, ETV6 LMNA 4408/4885SMN1; SMN2 4769/4885MAPT 1423/4885
US-20210111350-A1 PHOSPHORESCENT HOST COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE ORC3, CRY1, OSTC LMNA 4033/4885SMN1; SMN2 4480/4885MAPT 971/4885
US-20200168819-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP2E1 LMNA 1449/4885SMN1; SMN2 4396/4885MAPT 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.