SCHEMBL18164807

SCHEMBL18164807

O=S(=O)(Oc1c(N(c2ccccc2)c2cccc(-c3ccccc3)c2)cccc1N(c1ccccc1)c1cccc2c1oc1ccccc12)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NR1H3 Q13133 1/20 0.32
▸ CDC14B O60729 1/20 0.31
▸ CDC14A Q9UNH5 1/20 0.31
▸ PTGES2 Q9H7Z7 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ GGPS1 O95749 1/20 0.31
▸ PLA2G2A P14555 2/20 0.31
▸ PLA2G4A P47712 2/20 0.31
▸ ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18164786 0.84 SMN1; SMN2 (0.37) CDC14BCDC14ALMNAL3MBTL1
SCHEMBL17126317 0.84 ALOX5 (0.40) PTGES2LMNAGGPS1PLA2G2APLA2G4A
SCHEMBL14295689 0.82 ALOX5 (0.42) PTGES2LMNAGGPS1PLA2G2APLA2G4A
SCHEMBL24471688 0.82 ALOX5 (0.40) PTGES2LMNAGGPS1PLA2G2APLA2G4A
SCHEMBL14295685 0.82 ALOX5 (0.40) PTGES2LMNAGGPS1PLA2G2APLA2G4A
SCHEMBL14295691 0.81 ALOX5 (0.41) PTGES2LMNAGGPS1PLA2G2APLA2G4A
SCHEMBL14295705 0.81 PLA2G2A (0.39) PTGES2LMNAL3MBTL1GGPS1PLA2G2A
SCHEMBL24471723 0.81 ALOX5 (0.41) PTGES2LMNAGGPS1PLA2G2APLA2G4A
SCHEMBL24472295 0.81 ALOX5 (0.41) PTGES2LMNAGGPS1PLA2G2APLA2G4A
SCHEMBL14295687 0.81 ALOX5 (0.41) PTGES2LMNAGGPS1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180123048-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-03 — — US disclosed
WO-2016167491-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC APPARATUS 덕산네오룩스 주식회사 2016-10-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180123048-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 NR1H3 1404/4885CDC14B 4044/4885CDC14A 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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