SCHEMBL18166305

SCHEMBL18166305

Cc1ccc(-c2cc(OC(=O)NC(C)c3cnccn3)cc(-n3cnnn3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 5/20 0.53
P2RX2 Q9UBL9 5/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18166377 0.89 KMT2A (0.44) P2RX3P2RX2
SCHEMBL18166301 0.88 P2RX3 (0.51) P2RX3P2RX2
SCHEMBL18166298 0.88 P2RX3 (0.42) P2RX3P2RX2
SCHEMBL18166321 0.87 KMT2A (0.44) P2RX3P2RX2
SCHEMBL10243583 0.86 P2RX3 (0.69) P2RX3P2RX2
SCHEMBL18166425 0.85 KMT2A (0.44) P2RX3P2RX2
SCHEMBL18166309 0.85 KMT2A (0.46) P2RX3P2RX2
SCHEMBL18166422 0.84 P2RX3 (0.61) P2RX3P2RX2
SCHEMBL18166313 0.84 KMT2A (0.42) P2RX3P2RX2
SCHEMBL18166432 0.83 P2RX3 (0.59) P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2038264-B1 TETRAZOLE-SUBSTITUTED ARYLAMIDES HOFFMANN LA ROCHE (CH) 2016-10-26 EP claimed