Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166309 | 0.90 | KMT2A (0.46) | KMT2AP2RX3P2RX2KDM4EPOLB | |
| SCHEMBL18166305 | 0.89 | P2RX3 (0.53) | P2RX3P2RX2 | |
| SCHEMBL18166359 | 0.88 | P2RX3 (0.40) | KMT2AP2RX3P2RX2KDM4EPOLB | |
| SCHEMBL10243029 | 0.86 | P2RX3 (0.53) | P2RX3P2RX2PPARG | |
| SCHEMBL18166395 | 0.85 | KMT2A (0.41) | KMT2AP2RX3P2RX2KDM4EPOLB | |
| SCHEMBL18166425 | 0.84 | KMT2A (0.44) | KMT2AP2RX3P2RX2TDP1TSHR | |
| SCHEMBL18166321 | 0.84 | KMT2A (0.44) | KMT2AP2RX3P2RX2TSHRTP53 | |
| SCHEMBL18166449 | 0.84 | ACKR3 (0.38) | — | |
| SCHEMBL18166443 | 0.84 | MARS1 (0.43) | KMT2APOLBMAPT | |
| SCHEMBL18166313 | 0.83 | KMT2A (0.42) | KMT2AP2RX3P2RX2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |