Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.36 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | PRKACA | P17612 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | AKT2 | P31751 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166313 | 0.90 | KMT2A (0.42) | KMT2AP2RX3P2RX2CTSKTSHR | |
| SCHEMBL18166425 | 0.90 | KMT2A (0.44) | KMT2AP2RX3P2RX2CTSKTSHR | |
| SCHEMBL18166303 | 0.88 | ROCK1 (0.39) | KMT2AP2RX3P2RX2CTSKTSHR | |
| SCHEMBL18166305 | 0.87 | P2RX3 (0.53) | P2RX3P2RX2 | |
| SCHEMBL18166309 | 0.86 | KMT2A (0.46) | KMT2AP2RX3P2RX2CTSKTSHR | |
| SCHEMBL10243012 | 0.86 | P2RX3 (0.51) | P2RX3P2RX2TSHRROCK1PRKG1 | |
| SCHEMBL18166377 | 0.84 | KMT2A (0.44) | KMT2AP2RX3P2RX2TSHRTP53 | |
| SCHEMBL18166327 | 0.84 | ROCK1 (0.39) | CTSKTSHRPTGS2ROCK1PRKG1 | |
| SCHEMBL18166408 | 0.84 | MARS1 (0.46) | KMT2AROCK1ROCK2DGAT2 | |
| SCHEMBL18166395 | 0.83 | KMT2A (0.41) | KMT2AP2RX3P2RX2TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |