Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166454 | 0.91 | KMT2A (0.36) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL18166395 | 0.88 | KMT2A (0.41) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10243378 | 0.88 | CYP11B2 (0.38) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL18166298 | 0.84 | P2RX3 (0.42) | — | |
| SCHEMBL18036354 | 0.82 | KMT2A (0.39) | KMT2AMEN1MAPTESR1 | |
| SCHEMBL18166440 | 0.79 | MARS1 (0.40) | KMT2AMEN1MAPTALDH1A1F2 | |
| SCHEMBL18166443 | 0.79 | MARS1 (0.43) | KMT2AMEN1MAPTPOLBCTDSP1 | |
| SCHEMBL18166360 | 0.78 | CTSA (0.33) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL18166354 | 0.78 | KMT2A (0.38) | KMT2AMEN1ALDH1A1F2 | |
| SCHEMBL10243457 | 0.78 | P2RX3 (0.46) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |