Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166369 | 0.90 | P2RX3 (0.38) | CTSANPC1RAB9AWDR5P2RX7 | |
| SCHEMBL18166387 | 0.89 | TP53 (0.39) | CTSANPC1RAB9AWDR5SMN1; SMN2 | |
| SCHEMBL18166458 | 0.89 | P2RX3 (0.34) | CTSANPC1RAB9AWDR5POLB | |
| SCHEMBL10243831 | 0.88 | P2RX3 (0.40) | WDR5CYP11B2 | |
| SCHEMBL18166410 | 0.88 | P2RX3 (0.34) | CTSANPC1RAB9APOLBGAA | |
| SCHEMBL18166358 | 0.85 | P2RX3 (0.44) | WDR5 | |
| SCHEMBL18036334 | 0.83 | DGAT2 (0.36) | CTSAWDR5MEN1LMNAKMT2A | |
| SCHEMBL18036444 | 0.82 | DGAT2 (0.38) | CTSANPC1RAB9AWDR5SMN1; SMN2 | |
| SCHEMBL18166370 | 0.78 | KMT2A (0.36) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL10244060 | 0.78 | P2RX3 (0.51) | NPC1RAB9AWDR5CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |