Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166446 | 0.88 | P2RX3 (0.45) | P2RX3P2RX2 | |
| SCHEMBL18166435 | 0.87 | P2RX3 (0.48) | P2RX3P2RX2EPHX1SMN1; SMN2FAAH | |
| SCHEMBL18166430 | 0.84 | ADORA2A (0.41) | P2RX3P2RX2EPHX1SMN1; SMN2 | |
| SCHEMBL18166368 | 0.84 | P2RX3 (0.47) | P2RX3P2RX2EPHX1 | |
| SCHEMBL18166342 | 0.84 | P2RX3 (0.41) | P2RX3P2RX2KIT | |
| SCHEMBL18166275 | 0.83 | P2RX3 (0.38) | P2RX3P2RX2 | |
| SCHEMBL18166413 | 0.83 | P2RX3 (0.41) | P2RX3P2RX2EPHX1SMN1; SMN2TRPV1 | |
| SCHEMBL18166384 | 0.83 | P2RX3 (0.36) | P2RX3P2RX2EPHX1NPC1RAB9A | |
| SCHEMBL18166336 | 0.82 | P2RX3 (0.40) | P2RX3P2RX2SMN1; SMN2 | |
| SCHEMBL18166371 | 0.82 | P2RX3 (0.46) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |