Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166446 | 0.89 | P2RX3 (0.45) | P2RX3P2RX2 | |
| SCHEMBL18166398 | 0.87 | P2RX3 (0.57) | P2RX3P2RX2EPHX1HPGDSMEN1 | |
| SCHEMBL10244362 | 0.86 | P2RX3 (0.58) | P2RX3P2RX2 | |
| SCHEMBL18166413 | 0.86 | P2RX3 (0.41) | P2RX3P2RX2EPHX1L3MBTL1 | |
| SCHEMBL18166336 | 0.85 | P2RX3 (0.40) | P2RX3P2RX2 | |
| SCHEMBL18166376 | 0.84 | P2RX3 (0.39) | P2RX3P2RX2EPHX1 | |
| SCHEMBL18166432 | 0.84 | P2RX3 (0.59) | P2RX3P2RX2 | |
| SCHEMBL18166384 | 0.84 | P2RX3 (0.36) | P2RX3P2RX2EPHX1 | |
| SCHEMBL18166374 | 0.84 | P2RX3 (0.59) | P2RX3P2RX2 | |
| SCHEMBL18166322 | 0.84 | P2RX3 (0.59) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |