SCHEMBL1817005

SCHEMBL1817005

CCCCC1=C(c2ccccc2)C(=O)NC1=O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 5/20 0.46
▸ GSK3B P49841 4/20 0.44
▸ PARP1 P09874 1/20 0.41
▸ PTPN1 P18031 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ MMP2 P08253 4/20 0.38
▸ MMP9 P14780 4/20 0.38
▸ MMP8 P22894 2/20 0.38
▸ MMP13 P45452 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3671032 0.94 PTGS2 (0.44) PTGS2GSK3BPTPN1MMP2MMP9
SCHEMBL3719735 0.82 PTGS2 (0.51) PTGS2GSK3BMMP2MMP9
SCHEMBL9065563 0.78 GSK3B (0.52) PTGS2GSK3B
SCHEMBL27927888 0.77 MMP2 (0.44) PARP1MMP2MMP9MMP8MMP13
SCHEMBL27643712 0.75 ALDH1A1 (0.38) PARP1KDM4EMEN1KMT2A
SCHEMBL27287595 0.75 PTGS2 (0.50) PTGS2GSK3B
SCHEMBL7860145 0.75 GSK3B (0.49) PTGS2GSK3B
SCHEMBL2837669 0.74 PTPN1 (0.58) PTGS2GSK3BPTPN1MMP2MMP9
SCHEMBL28204385 0.74 ELANE (0.41) GSK3BPTPN1KDM4EMEN1KMT2A
SCHEMBL8754909 0.74 HSD11B1 (0.39) PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130198968-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS HERCULES LLC 2013-08-08 — — US claimed
EP-2545152-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS Isp Investments Inc. (US) 2013-01-16 — — EP claimed
WO-2011112944-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS ISP INVESTMENTS INC. (US) 2011-09-15 — — WO claimed
JP-61252211-A — — None — — JP disclosed
CN-108779213-A Methacrylic resin composition and formed body 旭化成株式会社 2018-11-09 — — CN disclosed
CN-104736373-B Cover for vehicle parts comprising methacrylic resin 旭化成株式会社 2018-11-06 — — CN disclosed
CN-108627979-A Head-mounted display component 旭化成株式会社 2018-10-09 — — CN disclosed
CN-108350125-A METHACRYLIC RESIN, METHACRYLIC RESIN COMPOSITION, FILM, AND PRODUCTION METHOD 旭化成株式会社 2018-07-31 — — CN disclosed
CN-107540779-A Methacrylic resin composition, the manufacture method of the Methacrylic resin composition, particle and formed body 旭化成株式会社 2018-01-05 — — CN disclosed
CN-107438648-A A kind of ferroelectricity adhesive composition 汉高股份有限及两合公司 2017-12-05 — — CN disclosed
EP-3235016-A1 A FERROELECTRIC ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2017-10-25 — — EP disclosed
WO-2011112944-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS ISP INVESTMENTS INC. (US) 2011-09-15 — — WO disclosed
WO-2011112944-A1 FUNCTIONAL ADDITIVES FOR CLEANSING COMPOSITIONS ISP INVESTMENTS INC. (US) 2011-09-15 — — WO disclosed
WO-2011063208-A1 ALKYL LACTAM ESTER POLYMERS, AND USES THEREOF ISP INVESTMENTS INC. (US) 2011-05-26 — — WO disclosed
WO-2009107880-A1 FLIP CHIP PACKAGING METHOD USING DOUBLE LAYER TYPE WAFER LEVEL UNDERFILL, FLIP CHIP PACKAGE MANUFACTURED USING THE SAME, AND SEMICONDUCTOR DEVICE FOR THE SAME LS MTRON, LTD. (KR) 2009-09-03 — — WO disclosed
EP-1461829-B1 DUAL CURE B-STAGEABLE UNDERFILL FOR WAFER LEVEL NAT STARCH CHEM INVEST (US) 2008-01-09 — — EP disclosed
CN-1307701-C B-stageable dual-cure wafer-level underfill NAT STARCH CHEM INVEST (US) 2007-03-28 — — CN disclosed
CN-1605122-A Dual cure B-stageable underfill for wafer level NAT STARCH CHEM INVEST (US) 2005-04-06 — — CN disclosed
US-6833629-B2 Compositions contain two separately curing chemistries; curing temperature ranges sufficiently separated to allow the first composition to cure without curing the second composition NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2004-12-21 — — US disclosed
JP-S61252211-A PRODUCTION OF HEAT-RESISTANT ACRYLIC RESIN OF GOOD OPTICAL PURITY ASAHI CHEM IND CO LTD 1986-11-10 — — JP disclosed
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