Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31501460 | 0.74 | EPHX1 (0.34) | — | |
| SCHEMBL28032871 | 0.73 | TDP1 (0.55) | TSHR | |
| SCHEMBL16365866 | 0.72 | CYP2D6 (0.39) | — | |
| SCHEMBL10625191 | 0.71 | TDP1 (0.52) | — | |
| SCHEMBL675683 | 0.69 | LTA4H (0.37) | TSHR | |
| SCHEMBL21873603 | 0.68 | TMEM97 (0.46) | — | |
| SCHEMBL7445883 | 0.68 | TSHR (0.52) | TSHR | |
| SCHEMBL19285124 | 0.66 | — | — | |
| SCHEMBL3481818 | 0.66 | LMNA (0.39) | — | |
| Ethylene SCHEMBL27544639 | 0.66 | LTA4H (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834526-B2 | HIV protease inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20160311786-A1 | HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311786-A1 | HIV PROTEASE INHIBITORS | PREP, PRSS1, CTSV | TSHR 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.