SCHEMBL1817099

SCHEMBL1817099

Cc1cccc(C)c1NC(=S)c1cccc(Br)c1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 4/20 0.53
LMNA P02545 3/20 0.53
MAPT P10636 3/20 0.53
RAB9A P51151 2/20 0.53
MEN1 O00255 3/20 0.53
HPGD P15428 1/20 0.53
ALOX12 P18054 1/20 0.53
CTSL P07711 3/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
CTSB P07858 1/20 0.43
GRM5 P41594 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1817366 0.80 GRM5 (0.60) KMT2AALDH1A1LMNAMAPTRAB9A
SCHEMBL28582383 0.77 HPGD (0.49) KMT2AALDH1A1LMNAMAPTRAB9A
SCHEMBL28582385 0.73 KMT2A (0.57) KMT2AALDH1A1LMNAMAPTRAB9A
SCHEMBL1814123 0.72 LMNA (0.63) KMT2ALMNAMEN1ALOX12GAA
SCHEMBL4737951 0.72 ALDH1A1 (0.47) KMT2AALDH1A1MAPTRAB9AMEN1
SCHEMBL20546806 0.71 KMT2A (0.48) KMT2AALDH1A1LMNAMAPTRAB9A
SCHEMBL12581572 0.71 GRM5 (0.57) KMT2AALDH1A1LMNAMAPTRAB9A
SCHEMBL28879914 0.70 C1S (0.52) KMT2AALDH1A1LMNARAB9AMEN1
SCHEMBL4741248 0.70 KDM4E (0.47) KMT2AALDH1A1LMNAMAPTRAB9A
SCHEMBL15484311 0.69 LMNA (0.69) KMT2AALDH1A1LMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10424745-B2 Organometallic complex, light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-09-24 US disclosed
US-20180212164-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-26 US disclosed
US-20180212164-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-26 US disclosed
EP-2496591-B1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2018-05-30 EP disclosed
EP-2496591-B1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2018-05-30 EP disclosed
US-20150287936-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
US-20150287936-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
US-20150287936-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
US-9065061-B2 Organometallic complex, light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-23 US disclosed
US-9065061-B2 Organometallic complex, light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-23 US disclosed
US-9065061-B2 Organometallic complex, light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-23 US disclosed
EP-2496591-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE Semiconductor Energy Laboratory Co. Ltd. (JP) 2012-09-12 EP disclosed
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-05 US disclosed
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-05 US disclosed
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-05 US disclosed
WO-2011052516-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-05-05 WO disclosed
WO-2011052516-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10424745-B2 Organometallic complex, light-emitting element, display device, electronic device, and lighting device GRK1, CDKL1, ARL1 KMT2A 2971/4885ALDH1A1 249/4885LMNA 3576/4885
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device GRK1, CDKL1, ARL1 KMT2A 2971/4885ALDH1A1 249/4885LMNA 3576/4885
US-20150287936-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device GRK1, CDKL1, ARL1 KMT2A 2971/4885ALDH1A1 249/4885LMNA 3576/4885
US-20180212164-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device GRK1, CDKL1, ARL1 KMT2A 2971/4885ALDH1A1 249/4885LMNA 3576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.