Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737951 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1GAARAB9AMAPT | |
| SCHEMBL11474720 | 0.73 | TAS1R3 (0.55) | LMNAALDH1A1GAAMAPTPDE4D | |
| SCHEMBL2764566 | 0.72 | ATM (0.61) | KDM4ESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL1817099 | 0.70 | KMT2A (0.53) | LMNASMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL1814123 | 0.69 | LMNA (0.63) | KDM4ELMNAGAAATMKMT2A | |
| SCHEMBL20064321 | 0.69 | ATM (0.49) | LMNAALDH1A1GAAATMKMT2A | |
| SCHEMBL4738279 | 0.69 | DUSP3 (0.71) | KDM4ELMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL16119698 | 0.68 | ATM (0.48) | LMNAALDH1A1GAAMAPTATM | |
| SCHEMBL4737919 | 0.68 | SMN1; SMN2 (0.48) | KDM4ELMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL10510032 | 0.67 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTPDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077170-A2 | BENZOTHIOAMIDES, AND USE THEREOF FOR RELAXING SMOOTH MUSCLES | Universität Wien (AT) | 2008-07-03 | — | — | WO | disclosed |