Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20445817 | 0.80 | RPS6KB1 (0.56) | RPS6KB1NUDT1RXFP1ARPGR | |
| SCHEMBL20445816 | 0.80 | RPS6KB1 (0.56) | RPS6KB1NUDT1RXFP1ARPGR | |
| SCHEMBL18171880 | 0.77 | NUDT1 (0.42) | RPS6KB1NUDT1ARSRCPGR | |
| SCHEMBL18171862 | 0.71 | L3MBTL1 (0.43) | PABPC1RPS6KB1NUDT1LMNAL3MBTL1 | |
| SCHEMBL18176360 | 0.70 | RPS6KB1 (0.79) | RPS6KB1 | |
| Hydrochloric Acid SCHEMBL18171888 | 0.69 | RPS6KB1 (0.78) | RPS6KB1 | |
| SCHEMBL27449699 | 0.67 | SRC (0.42) | NUDT1SRC | |
| SCHEMBL780421 | 0.65 | NUDT1 (0.47) | NUDT1ARHTT | |
| SCHEMBL27851794 | 0.65 | NUDT1 (0.47) | NUDT1ARHTT | |
| SCHEMBL18171887 | 0.65 | NUDT1 (0.47) | NUDT1ARHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |