Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782016 | 0.77 | ROCK2 (0.42) | NUDT1RPS6KB1 | |
| SCHEMBL780600 | 0.77 | ROCK2 (0.42) | NUDT1RPS6KB1 | |
| SCHEMBL20572016 | 0.77 | ROCK2 (0.42) | NUDT1RPS6KB1 | |
| SCHEMBL18171864 | 0.77 | PABPC1 (0.42) | NUDT1ARPGRJAK2JAK3 | |
| SCHEMBL20445816 | 0.76 | RPS6KB1 (0.56) | NUDT1ARPGRJAK2JAK3 | |
| SCHEMBL20445817 | 0.76 | RPS6KB1 (0.56) | NUDT1ARPGRJAK2JAK3 | |
| SCHEMBL21842694 | 0.76 | NUDT1 (0.38) | NUDT1ARPGRJAK2JAK3 | |
| SCHEMBL18171876 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL780421 | 0.75 | NUDT1 (0.47) | NUDT1ARMEN1MAPTKMT2A | |
| SCHEMBL27851794 | 0.75 | NUDT1 (0.47) | NUDT1ARMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |