Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 6/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20445835 | 0.83 | RPS6KB1 (0.48) | IDH1RPS6KB1 | |
| SCHEMBL20445801 | 0.83 | RPS6KB1 (0.48) | IDH1RPS6KB1 | |
| SCHEMBL18171882 | 0.81 | NUDT1 (0.40) | LPLLIPG | |
| SCHEMBL29002570 | 0.76 | SOS1 (0.56) | EGFR | |
| SCHEMBL18171862 | 0.75 | L3MBTL1 (0.43) | RPS6KB1EGFRLCKADORA2AADORA2B | |
| SCHEMBL24576525 | 0.74 | GALR3 (0.58) | EGFR | |
| SCHEMBL29775101 | 0.74 | GALR3 (0.58) | EGFR | |
| SCHEMBL24576519 | 0.74 | GALR3 (0.58) | EGFR | |
| SCHEMBL5803847 | 0.73 | LPL (0.54) | LPLLIPG | |
| SCHEMBL17439241 | 0.73 | LIPG (0.43) | LPLLIPGIDH1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |