Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18172071 | 0.74 | PDE2A (0.49) | ALDH1A1GAAKDM4EHTT | |
| SCHEMBL18172029 | 0.74 | KMT2A (0.50) | ALDH1A1PKML3MBTL1GAAKMT2A | |
| SCHEMBL6033804 | 0.72 | KMT2A (0.53) | ALDH1A1GAAKMT2AUSP2MAPT | |
| SCHEMBL4452273 | 0.72 | ALDH1A1 (0.56) | ALDH1A1PKML3MBTL1GAAKMT2A | |
| SCHEMBL29106434 | 0.69 | KMT2A (0.42) | ALDH1A1L3MBTL1GAAKMT2AMAPK1 | |
| SCHEMBL31064634 | 0.69 | KMT2A (0.46) | ALDH1A1PKMGAAKMT2AMAPK1 | |
| SCHEMBL30134103 | 0.69 | KMT2A (0.46) | ALDH1A1PKMGAAKMT2AMAPK1 | |
| SCHEMBL12303237 | 0.69 | KMT2A (0.44) | ALDH1A1PKML3MBTL1GAAKMT2A | |
| SCHEMBL13754130 | 0.69 | MAPK1 (0.70) | ALDH1A1PKML3MBTL1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL31064662 | 0.68 | KMT2A (0.41) | ALDH1A1L3MBTL1GAAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286178-A1 | AMINO-SUBSTITUTED HETEROCYCLIC DERIVATIVES AS SODIUM CHANNEL INHIBITORS | Almirall S.A. (ES) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016170009-A1 | AMINO-SUBSTITUTED HETEROCYCLIC DERIVATIVES AS SODIUM CHANNEL INHIBITORS | ALMIRALL, S.A. (ES) | 2016-10-27 | — | — | WO | disclosed |