Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.61 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | PDE2A | O00408 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.59 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.57 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19837832 | 0.88 | AHCY (0.73) | AHCYADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL13183211 | 0.86 | ADORA3 (0.71) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL15371600 | 0.84 | AHCY (1.00) | AHCYADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL26807050 | 0.84 | AHCY (1.00) | AHCYADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL16682237 | 0.84 | AHCY (1.00) | AHCYADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6886946 | 0.84 | ADORA3 (0.81) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL6837087 | 0.84 | ADORA3 (0.81) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL20128458 | 0.84 | ADORA3 (0.81) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL8975371 | 0.84 | ADORA3 (0.76) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL4535914 | 0.84 | ADORA3 (0.81) | ADORA3CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037601-A1 | Nucleoside-Based Anti-Bacterial and Anti-Protozoan Drugs | UTI LIMITED PARTNERSHIP (CA) | 2018-02-08 | — | — | US | disclosed |
| WO-2016168911-A1 | NUCLEOSIDE-BASED ANTI-BACTERIAL AND ANTI-PROTOZOAN DRUGS | UTI LIMITED PARTNERSHIP (CA) | 2016-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037601-A1 | Nucleoside-Based Anti-Bacterial and Anti-Protozoan Drugs | PNP, NUDT1, SLC29A1 | AHCY 1682/4885ADORA3 78/4885CA1 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.