SCHEMBL18173520

SCHEMBL18173520

[N-]=[N+]=NS(=O)(=O)c1ccccc1N1C(=O)CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.34
CA7 P43166 2/20 0.34
PARL Q9H300 3/20 0.33
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
MAPK1 P28482 1/20 0.33
RAF1 P04049 1/20 0.33
MAPK3 P27361 1/20 0.33
MAP3K8 P41279 1/20 0.33
MAP2K1 Q02750 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 1/20 0.33
CA1 P00915 2/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18171722 0.83 TLR9 (0.48) CA2CA7CA12CA9CA1
SCHEMBL2850335 0.82 CA2 (0.44) CA2CA7CA12CA9GAA
SCHEMBL11031360 0.80 MYC (0.37) CA2CA7CYP3A4CYP2C9TSHR
SCHEMBL10616438 0.76 GAA (0.34) CA2CA7CA12CA9GAA
SCHEMBL11392875 0.74 CA2 (0.42) CA2CA7PARLCA12CA9
SCHEMBL27524195 0.74 MYC (0.51) CA2CA7PARLCA12CA9
SCHEMBL18173521 0.72 ALDH1A1 (0.44) CA2PARLCA12CA9GAA
SCHEMBL18173518 0.72 CA12 (0.56) CA2CA12CA9GAAKMT2A
SCHEMBL6341570 0.70 TLR9 (0.52) PARLCA12CA9MAPK1RAF1
SCHEMBL6541922 0.68 NFE2L2 (0.40) GAAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10100133-B2 Process for functionalising polymers AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2018-10-16 US claimed
US-20180118857-A1 PROCESS FOR FUNCTIONALISING POLYMERS WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2018-05-03 US claimed
EP-3286252-A1 PROCESS FOR FUNCTIONALISING POLYMERS Akzo Nobel Chemicals International B.V. (NL) 2018-02-28 EP claimed
CN-107531909-A The method of functionalized polymeric 阿克苏诺贝尔化学品国际有限公司 2018-01-02 CN claimed
WO-2016170019-A1 PROCESS FOR FUNCTIONALISING POLYMERS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-10-27 WO claimed
US-10100133-B2 Process for functionalising polymers AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2018-10-16 US disclosed
US-20180118857-A1 PROCESS FOR FUNCTIONALISING POLYMERS WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2018-05-03 US disclosed
EP-3286252-A1 PROCESS FOR FUNCTIONALISING POLYMERS Akzo Nobel Chemicals International B.V. (NL) 2018-02-28 EP disclosed
CN-107531909-A The method of functionalized polymeric 阿克苏诺贝尔化学品国际有限公司 2018-01-02 CN disclosed
WO-2016170019-A1 PROCESS FOR FUNCTIONALISING POLYMERS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-10-27 WO disclosed