Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13429466 | 0.89 | MGAM (0.41) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL11921768 | 0.87 | LDHA (0.50) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL26202990 | 0.85 | ADRA1A (0.40) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL10033437 | 0.85 | PHF8 (0.46) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL13219609 | 0.82 | KDM4E (0.40) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL13392107 | 0.80 | MGAM (0.35) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL13219606 | 0.80 | MEN1 (0.48) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL12521999 | 0.79 | LDHA (0.42) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL9967369 | 0.79 | MGAM (0.38) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL13113008 | 0.78 | TGFBR1 (0.37) | KDM4ELDHASRRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475758-B2 | Compounds, method for preparation thereof and use thereof for preparing polymers useful for increasing heat resistance of polymeric compositions | FAURECIA INTERIEUR INDUSTRIE (FR) | 2016-10-25 | — | — | US | disclosed |