SCHEMBL18174538

SCHEMBL18174538

CC1(C)c2ccccc2-c2cnccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
HTR2A P28223 2/20 0.38
MLNR O43193 1/20 0.38
NR1I2 O75469 1/20 0.38
CHRM2 P08172 1/20 0.38
ADRB1 P08588 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD2 P14416 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
CHRM3 P20309 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174532 0.88 MAOA (0.44) MAOAMAOBHTR2AMLNRNR1I2
SCHEMBL21453509 0.85 MAOA (0.56) MAOAMAOBADRA1AKCNH2KCNQ2
SCHEMBL22414000 0.85 MAOA (0.41) MAOAMAOBKCNQ2CYP1A2CYP3A4
SCHEMBL19009209 0.83 MAOA (0.47) MAOAMAOBKCNQ2CYP1A2CYP3A4
SCHEMBL30322811 0.83 MAOA (0.47) MAOAMAOBKCNQ2CYP1A2CYP3A4
SCHEMBL19009212 0.83 MAOA (0.47) MAOAMAOBKCNQ2CYP1A2CYP3A4
SCHEMBL22424778 0.80 MAOA (0.44) MAOAMAOBKCNQ2CYP1A2CYP3A4
SCHEMBL283246 0.80 HTR2A (0.48) HTR2AMLNRNR1I2CHRM2ADRB1
SCHEMBL29363404 0.80 HTR2A (0.48) HTR2AMLNRNR1I2CHRM2ADRB1
SCHEMBL19886873 0.78 MAOA (0.42) MAOAMAOBKCNQ2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-20230303537-A1 NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-28 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
CN-111349055-B Polycyclic compound used as electroluminescent material and application thereof 烟台显华光电材料研究院有限公司 2023-04-21 CN disclosed
US-20200274081-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
CN-111349055-A Polycyclic compound used as electroluminescent material and application thereof 烟台显华光电材料研究院有限公司 2020-06-30 CN disclosed
US-20160329509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2016-11-10 US disclosed
US-20160329509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2016-11-10 US disclosed
US-9478758-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-10-25 US disclosed
US-9478758-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230389413-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 MAOA 4628/4885MAOB 4557/4885HTR2A 4447/4885
US-20200274081-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 MAOA 4628/4885MAOB 4557/4885HTR2A 4447/4885
US-20160329509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, SLC25A21, SLC25A11 MAOA 150/4885MAOB 254/4885HTR2A 3089/4885
US-20230303537-A1 NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF NPM1, NFE2L2, MNS1 MAOA 1846/4885MAOB 1449/4885HTR2A 2565/4885
US-11758807-B2 Organic electroluminescent materials and devices GLRA3, ESRRG, GLRA1 MAOA 4628/4885MAOB 4557/4885HTR2A 4447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.