SCHEMBL18174576

SCHEMBL18174576

Cc1cc(-c2c3ccccc3c(-c3ccc(-c4ccccn4)c(C)c3)c3cc(-c4ccccc4)ccc23)ccc1-c1ccccn1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 1/20 0.37
GRM5 P41594 3/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
BRD4 O60885 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.36
KLF5 Q13887 1/20 0.36
MAPK1 P28482 1/20 0.36
BTK Q06187 1/20 0.35
PIK3CA P42336 1/20 0.35
DHODH Q02127 1/20 0.35
TGFBR1 P36897 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15160908 1.00 KDM4E (0.37) KDM4ENPC1GRM5TSHRHSD17B10
SCHEMBL15160992 0.97 GRM5 (0.37) KDM4ENPC1GRM5TSHRHSD17B10
SCHEMBL15160964 0.90 NPC1 (0.44) KDM4ENPC1GRM5TSHRSMN1; SMN2
SCHEMBL18174575 0.90 DHODH (0.40) KDM4ENPC1GRM5TSHRHSD17B10
SCHEMBL18174583 0.90 BTK (0.38) KDM4ENPC1GRM5TSHRHSD17B10
SCHEMBL18174594 0.89 KDM4E (0.42) KDM4ENPC1TSHRHSD17B10SMN1; SMN2
SCHEMBL18633527 0.87 KDM4E (0.46) KDM4ENPC1GRM5TSHRHSD17B10
SCHEMBL18174612 0.87 DHODH (0.39) KDM4ENPC1GRM5TSHRHSD17B10
SCHEMBL15161038 0.85 IMPDH2 (0.38) KDM4ENPC1GRM5HSD17B10SMN1; SMN2
SCHEMBL18174673 0.85 WNT3A (0.44) KDM4ENPC1TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed