SCHEMBL18174673

SCHEMBL18174673

Cc1cc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccccn5)c(C)c4)c4ccccc34)cc2)ccn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WNT3A P56704 7/20 0.44
PDK2 Q15119 1/20 0.42
MAP4K4 O95819 2/20 0.41
CDC7 O00311 1/20 0.41
ROCK2 O75116 1/20 0.41
CDK2 P24941 1/20 0.41
GSK3B P49841 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
MKNK2 Q9HBH9 1/20 0.41
IRAK4 Q9NWZ3 1/20 0.41
DYRK1A Q13627 1/20 0.40
TGFBR1 P36897 2/20 0.39
PSEN1 P49768 2/20 0.36
PSEN2 P49810 2/20 0.36
APH1B Q8WW43 2/20 0.36
NCSTN Q92542 2/20 0.36
APH1A Q96BI3 2/20 0.36
PSENEN Q9NZ42 2/20 0.36
PORCN Q9H237 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174650 0.91 WNT3A (0.45) WNT3APDK2MAP4K4CDC7ROCK2
SCHEMBL15161038 0.88 IMPDH2 (0.38) WNT3ATGFBR1KDM4ENPC1
SCHEMBL15160964 0.88 NPC1 (0.44) PDK2TGFBR1KDM4ENPC1
SCHEMBL18174701 0.85 WNT3A (0.37) WNT3ATGFBR1KDM4ENPC1
SCHEMBL18174639 0.85 PIK3CA (0.44) WNT3APDK2MAP4K4CDC7ROCK2
SCHEMBL15160908 0.85 KDM4E (0.37) TGFBR1KDM4ENPC1
SCHEMBL18174576 0.85 KDM4E (0.37) TGFBR1KDM4ENPC1
SCHEMBL18174722 0.85 WNT3A (0.47) WNT3APDK2IRAK4DYRK1ATGFBR1
SCHEMBL18174662 0.83 DYRK1A (0.43) WNT3APDK2MAP4K4CDC7ROCK2
SCHEMBL15160992 0.82 GRM5 (0.37) PDK2MAP4K4TGFBR1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed