SCHEMBL18174643

SCHEMBL18174643

Cc1cc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccnc5)c(C)c4)c4ccccc34)cc2)ccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PORCN Q9H237 3/20 0.47
PSEN1 P49768 2/20 0.47
PSEN2 P49810 2/20 0.47
APH1B Q8WW43 2/20 0.47
NCSTN Q92542 2/20 0.47
APH1A Q96BI3 2/20 0.47
PSENEN Q9NZ42 2/20 0.47
SLC2A1 P11166 1/20 0.47
WNT3A P56704 3/20 0.46
PDE3B Q13370 1/20 0.42
PDE3A Q14432 1/20 0.42
MKNK2 Q9HBH9 2/20 0.41
MKNK1 Q9BUB5 1/20 0.41
DYRK1A Q13627 2/20 0.41
DYRK1B Q9Y463 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP2E1 P05181 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2A6 P11509 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174652 0.93 PORCN (0.47) PORCNPSEN1PSEN2APH1BNCSTN
SCHEMBL18174782 0.90 PORCN (0.49) PORCNPSEN1PSEN2APH1BNCSTN
SCHEMBL18174694 0.88 SLC2A1 (0.49) SLC2A1WNT3APDE3BPDE3AMKNK2
SCHEMBL18174639 0.88 PIK3CA (0.44) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL18174763 0.88 PSEN1 (0.54) PORCNPSEN1PSEN2APH1BNCSTN
SCHEMBL18174559 0.87 SLC2A1 (0.54) SLC2A1PDE3BPDE3AMKNK2MKNK1
SCHEMBL15160968 0.85 SLC2A1 (0.51) SLC2A1PDE3BPDE3AMKNK2MKNK1
SCHEMBL18174662 0.84 DYRK1A (0.43) PORCNPSEN1PSEN2APH1BNCSTN
SCHEMBL18174728 0.83 DYRK1A (0.43) PORCNPSEN1PSEN2APH1BNCSTN
SCHEMBL18174679 0.83 SLC2A1 (0.46) SLC2A1WNT3APDE3BPDE3AMKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed