SCHEMBL18174763

SCHEMBL18174763

Cc1cc(-c2ccc(-c3c4ccccc4c(-c4cccc(-c5cccnc5)c4)c4ccccc34)cc2)ccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 4/20 0.54
PSEN2 P49810 4/20 0.54
APH1B Q8WW43 4/20 0.54
NCSTN Q92542 4/20 0.54
APH1A Q96BI3 4/20 0.54
PSENEN Q9NZ42 4/20 0.54
PORCN Q9H237 2/20 0.51
WNT3A P56704 2/20 0.49
PIK3CA P42336 1/20 0.44
CYP17A1 P05093 1/20 0.43
CYP19A1 P11511 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
DYRK1A Q13627 2/20 0.42
TLR9 Q9NR96 1/20 0.42
TLR8 Q9NR97 1/20 0.42
TLR7 Q9NYK1 1/20 0.42
CHEK1 O14757 1/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174731 0.91 WNT3A (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL18174738 0.90 DYRK1A (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL15160979 0.89 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL18174652 0.88 PORCN (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL18174643 0.88 PORCN (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL10030085 0.87 CYP11B1 (0.54) CYP17A1CYP19A1CYP11B1CYP11B2DYRK1A
SCHEMBL15161067 0.87 WNT3A (0.45) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL18174757 0.87 WNT3A (0.45) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL18174782 0.87 PORCN (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL10030096 0.86 CYP11B1 (0.50) PIK3CACYP17A1CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed