SCHEMBL18174652

SCHEMBL18174652

Cc1cc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccnc5)cc4C)c4ccccc34)cc2)ccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PORCN Q9H237 2/20 0.47
WNT3A P56704 2/20 0.46
PSEN1 P49768 1/20 0.45
PSEN2 P49810 1/20 0.45
APH1B Q8WW43 1/20 0.45
NCSTN Q92542 1/20 0.45
APH1A Q96BI3 1/20 0.45
PSENEN Q9NZ42 1/20 0.45
SLC2A1 P11166 1/20 0.45
PIK3CA P42336 1/20 0.43
MKNK2 Q9HBH9 2/20 0.41
MKNK1 Q9BUB5 1/20 0.41
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
MAP4K4 O95819 2/20 0.39
GSK3B P49841 2/20 0.39
CLK4 Q9HAZ1 2/20 0.39
TLR9 Q9NR96 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174643 0.93 PORCN (0.47) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL18174782 0.90 PORCN (0.49) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL18174679 0.90 SLC2A1 (0.46) WNT3ASLC2A1PIK3CAMKNK2MKNK1
SCHEMBL18174662 0.89 DYRK1A (0.43) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL18174763 0.88 PSEN1 (0.54) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL18174556 0.87 SLC2A1 (0.54) SLC2A1PIK3CAMKNK2MKNK1CYP17A1
SCHEMBL18174707 0.84 SLC2A1 (0.46) SLC2A1MKNK2MKNK1CYP17A1CYP19A1
SCHEMBL18174693 0.84 MAPK14 (0.38) WNT3ASLC2A1PIK3CAMKNK2MKNK1
SCHEMBL18174573 0.84 SLC2A1 (0.49) SLC2A1PIK3CAMKNK2MKNK1CYP17A1
SCHEMBL18174726 0.83 SLC2A1 (0.47) SLC2A1PIK3CAMKNK2MKNK1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed