SCHEMBL18174650

SCHEMBL18174650

Cc1cc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccccn5)cc4C)c4ccccc34)cc2)ccn1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
WNT3A P56704 7/20 0.45
PDK2 Q15119 2/20 0.41
MAP4K4 O95819 2/20 0.40
CDC7 O00311 1/20 0.40
ROCK2 O75116 1/20 0.40
CDK2 P24941 1/20 0.40
GSK3B P49841 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
IRAK4 Q9NWZ3 1/20 0.40
DYRK1A Q13627 1/20 0.40
RET P07949 1/20 0.37
RIPK1 Q13546 1/20 0.37
RIPK3 Q9Y572 1/20 0.37
DHODH Q02127 1/20 0.36
TGFBR1 P36897 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174673 0.91 WNT3A (0.44) WNT3APDK2MAP4K4CDC7ROCK2
SCHEMBL18174662 0.87 DYRK1A (0.43) WNT3APDK2MAP4K4CDC7ROCK2
SCHEMBL18174558 0.87 KDM4E (0.44) WNT3APDK2IRAK4RETRIPK1
SCHEMBL18174722 0.86 WNT3A (0.47) WNT3APDK2IRAK4DYRK1ATGFBR1
SCHEMBL18174708 0.85 WNT3A (0.39) WNT3APDK2IRAK4RETRIPK1
SCHEMBL18174575 0.84 DHODH (0.40) PDK2RETRIPK1RIPK3DHODH
SCHEMBL18174652 0.82 PORCN (0.47) WNT3AMAP4K4CDC7ROCK2CDK2
SCHEMBL9612984 0.82 DYRK1A (0.45) WNT3APDK2MAP4K4CDC7ROCK2
SCHEMBL18174743 0.82 DYRK1A (0.47) WNT3APDK2MAP4K4CDC7ROCK2
SCHEMBL18174696 0.81 DHODH (0.47) PDK2MKNK2RETRIPK1RIPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed