SCHEMBL9612943

SCHEMBL9612943

Cc1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cncc(C)c5)cc4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.39
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
COMT P21964 1/20 0.38
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
ACHE P22303 1/20 0.36
CDK7 P50613 1/20 0.35
ENPP1 P22413 1/20 0.35
TDO2 P48775 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
PTGS2 P35354 1/20 0.34
GBA1 P04062 1/20 0.34
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34
ADK P55263 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174764 0.94 CYP2A6 (0.41) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL18174777 0.92 CYP2A6 (0.40) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL15161112 0.88 CYP2A6 (0.47) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL15161110 0.88 CYP11B1 (0.44) CYP2A6CYP11B1CYP11B2GPR84PTGS2
SCHEMBL10017308 0.87 CYP2A6 (0.41) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL18174769 0.87 PDK2 (0.36) CYP2A6S1PR1S1PR3COMTCYP11B1
SCHEMBL9612921 0.84 DHFR (0.40) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL9612928 0.84 CYP2A6 (0.38) CYP2A6S1PR1S1PR3CYP11B1CYP11B2
SCHEMBL18174790 0.84 WNT3A (0.42) CYP2A6TDO2
SCHEMBL18174766 0.84 TDO2 (0.37) CYP2A6S1PR1S1PR3COMTCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed