Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004019 | 0.81 | SIRT1 (0.42) | NR3C1KDM4EALOX15TSHRSIRT1 | |
| SCHEMBL17108088 | 0.81 | P2RX7 (0.47) | HTR7NR3C1SIRT1MAPTKMT2A | |
| SCHEMBL18176034 | 0.80 | NR3C1 (0.58) | NR3C1DRD3KDM4EALOX15TSHR | |
| SCHEMBL17108104 | 0.79 | NR3C1 (0.39) | HTR7NR3C1DRD2DRD4DRD3 | |
| SCHEMBL17108103 | 0.79 | MAPK1 (0.39) | NR3C1HDAC1HDAC7KDM4EALOX15 | |
| SCHEMBL7690504 | 0.78 | ALDH1A1 (0.54) | HTR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7479380 | 0.71 | PDE4A (0.41) | HTR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1857368 | 0.70 | BCHE (0.41) | HTR7NR3C1DRD2DRD3KDM4E | |
| SCHEMBL11458214 | 0.69 | NR3C1 (0.53) | NR3C1DRD3KDM4EALOX15TSHR | |
| SCHEMBL28221824 | 0.69 | KDM4E (0.69) | KDM4EALOX15TSHRSIRT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906661-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-10-26 | — | — | EP | disclosed |