Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 2/20 | 0.75 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.75 |
| ▸ | BTK | Q06187 | 16/20 | 0.66 |
| ▸ | LCK | P06239 | 7/20 | 0.66 |
| ▸ | LYN | P07948 | 5/20 | 0.66 |
| ▸ | SRC | P12931 | 7/20 | 0.58 |
| ▸ | FYN | P06241 | 4/20 | 0.58 |
| ▸ | FLT3 | P36888 | 4/20 | 0.58 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.58 |
| ▸ | EGFR | P00533 | 4/20 | 0.58 |
| ▸ | HCK | P08631 | 3/20 | 0.58 |
| ▸ | FGR | P09769 | 3/20 | 0.58 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.58 |
| ▸ | BRAF | P15056 | 3/20 | 0.58 |
| ▸ | ITK | Q08881 | 3/20 | 0.58 |
| ▸ | YES1 | P07947 | 2/20 | 0.58 |
| ▸ | BLK | P51451 | 2/20 | 0.58 |
| ▸ | BMX | P51813 | 2/20 | 0.58 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.58 |
| ▸ | RET | P07949 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22778897 | 0.87 | SRC (0.68) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL130529 | 0.86 | NUDT14 (1.00) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25937452 | 0.83 | NUDT14 (0.69) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL24192635 | 0.83 | NUDT14 (0.72) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25069189 | 0.83 | NUDT14 (0.72) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25069027 | 0.83 | SRC (0.76) | NUDT14NUDT5LCKSRCEGFR | |
| SCHEMBL24196500 | 0.83 | NUDT14 (0.69) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL3617461 | 0.83 | SRC (0.79) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL13861437 | 0.82 | BTK (0.72) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL28407363 | 0.82 | BTK (0.89) | NUDT14NUDT5BTKLCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170545-A1 | PROCESS FOR THE PREPARATION OF 1-[(3R)-3-[4-AMINO-3-(4-PHENOXYPHENVL)-1H- PVRAZOLO[3,4-D]PYRINIIDIN-1-Y1]-1-PIPERIDINVL]-2-PROPEN-1-ONE AND ITS POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED (IN) | 2016-10-27 | — | — | WO | disclosed |