Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 2/20 | 0.69 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.69 |
| ▸ | BTK | Q06187 | 16/20 | 0.61 |
| ▸ | LCK | P06239 | 7/20 | 0.61 |
| ▸ | LYN | P07948 | 5/20 | 0.61 |
| ▸ | SRC | P12931 | 7/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | TEK | Q02763 | 2/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 4/20 | 0.52 |
| ▸ | FLT3 | P36888 | 4/20 | 0.52 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.52 |
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | HCK | P08631 | 3/20 | 0.52 |
| ▸ | FGR | P09769 | 3/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24192635 | 0.88 | NUDT14 (0.72) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL24196500 | 0.88 | NUDT14 (0.69) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25466526 | 0.85 | NUDT14 (0.68) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL24196427 | 0.85 | NUDT14 (0.68) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25951904 | 0.83 | SRC (0.53) | NUDT14NUDT5BTKLYNSRC | |
| SCHEMBL18176199 | 0.83 | NUDT14 (0.75) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL130529 | 0.81 | NUDT14 (1.00) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL3617461 | 0.79 | SRC (0.79) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25069189 | 0.79 | NUDT14 (0.72) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25069027 | 0.79 | SRC (0.76) | NUDT14NUDT5LCKSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248833-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248833-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | BTK, WEE1, WEE2 | NUDT14 3438/4885NUDT5 3516/4885BTK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.