Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 2/20 | 0.72 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.72 |
| ▸ | BTK | Q06187 | 16/20 | 0.61 |
| ▸ | LCK | P06239 | 8/20 | 0.61 |
| ▸ | LYN | P07948 | 4/20 | 0.61 |
| ▸ | SRC | P12931 | 6/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | TEK | Q02763 | 3/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | PRKDC | P78527 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 4/20 | 0.52 |
| ▸ | ITK | Q08881 | 3/20 | 0.52 |
| ▸ | BMX | P51813 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | JAK3 | P52333 | 2/20 | 0.52 |
| ▸ | HCK | P08631 | 3/20 | 0.52 |
| ▸ | FGR | P09769 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937452 | 0.88 | NUDT14 (0.69) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL24196500 | 0.88 | NUDT14 (0.69) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL24196427 | 0.87 | NUDT14 (0.68) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25466526 | 0.87 | NUDT14 (0.68) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL130529 | 0.84 | NUDT14 (1.00) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL18176199 | 0.83 | NUDT14 (0.75) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL3617461 | 0.81 | SRC (0.79) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25069027 | 0.81 | SRC (0.76) | NUDT14NUDT5LCKSRCKDR | |
| SCHEMBL25069189 | 0.81 | NUDT14 (0.72) | NUDT14NUDT5BTKLCKLYN | |
| SCHEMBL25479854 | 0.78 | BTK (0.69) | NUDT14NUDT5BTKLCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022007824-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | 四川海思科制药有限公司 | 2022-01-13 | — | — | WO | disclosed |