SCHEMBL1817674

SCHEMBL1817674

CC(=S)N(c1ccccc1)c1c(C)cccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TSHR P16473 1/20 0.46
ALDH1A1 P00352 5/20 0.45
GAA P10253 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
FAAH O00519 1/20 0.41
PHGDH O43175 1/20 0.41
MGLL Q99685 1/20 0.41
NPSR1 Q6W5P4 1/20 0.39
HTT P42858 2/20 0.39
GLA P06280 1/20 0.39
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
LMNA P02545 1/20 0.36
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7521817 0.81 ALDH1A1 (0.58) MEN1KMT2ATSHRALDH1A1GAA
SCHEMBL17438142 0.78 KMT2A (0.51) MEN1KMT2ATSHRALDH1A1L3MBTL1
SCHEMBL22601052 0.73 TSHR (0.41) MEN1KMT2ATSHRALDH1A1GAA
SCHEMBL9870757 0.71 LMNA (0.41) MEN1KMT2ATSHRALDH1A1GAA
SCHEMBL7883806 0.70 TSHR (0.43) MEN1KMT2ATSHRALDH1A1L3MBTL1
O-Xylene SCHEMBL27862983 0.69 ACHE (0.62) TSHRALDH1A1GAAMAPTHPGD
SCHEMBL6768370 0.69 ALDH1A1 (0.54) MEN1KMT2AALDH1A1GAAL3MBTL1
SCHEMBL15362296 0.69 TSHR (0.41) MEN1KMT2ATSHRALDH1A1FAAH
SCHEMBL14354423 0.68 ALDH1A1 (0.44) MEN1KMT2ATSHRALDH1A1GAA
SCHEMBL17956796 0.68 ALDH1A1 (0.64) MEN1KMT2ATSHRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10424745-B2 Organometallic complex, light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-09-24 US disclosed
US-20180212164-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-26 US disclosed
EP-2496591-B1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2018-05-30 EP disclosed
US-20150287936-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
US-9065061-B2 Organometallic complex, light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-23 US disclosed
EP-2496591-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE Semiconductor Energy Laboratory Co. Ltd. (JP) 2012-09-12 EP disclosed
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-05 US disclosed
WO-2011052516-A1 ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10424745-B2 Organometallic complex, light-emitting element, display device, electronic device, and lighting device GRK1, CDKL1, ARL1 MEN1 907/4885KMT2A 2971/4885TSHR 2966/4885
US-20110101854-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device GRK1, CDKL1, ARL1 MEN1 907/4885KMT2A 2971/4885TSHR 2966/4885
US-20150287936-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device GRK1, CDKL1, ARL1 MEN1 907/4885KMT2A 2971/4885TSHR 2966/4885
US-20180212164-A1 Organometallic Complex, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device GRK1, CDKL1, ARL1 MEN1 907/4885KMT2A 2971/4885TSHR 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.