Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1058052 | 0.80 | TSHR (0.38) | LMNATSHRACHESIGMAR1CYP3A4 | |
| SCHEMBL30716542 | 0.80 | ALDH1A1 (0.50) | LMNATSHRACHESIGMAR1CYP3A4 | |
| SCHEMBL141725 | 0.80 | ALDH1A1 (0.50) | LMNATSHRACHESIGMAR1CYP3A4 | |
| SCHEMBL9871045 | 0.79 | MEN1 (0.40) | LMNATSHRCYP3A4ALDH1A1MAPT | |
| Lithium Ion SCHEMBL9355801 | 0.78 | CA12 (0.39) | LMNATSHRACHESIGMAR1CYP3A4 | |
| SCHEMBL16628602 | 0.78 | CA12 (0.39) | LMNATSHRACHESIGMAR1CYP3A4 | |
| SCHEMBL16628430 | 0.78 | CA12 (0.39) | LMNATSHRACHESIGMAR1CYP3A4 | |
| Potassium Ion SCHEMBL9356020 | 0.78 | CA12 (0.39) | LMNATSHRACHESIGMAR1CYP3A4 | |
| Zinc Ion SCHEMBL941335 | 0.78 | CA12 (0.39) | LMNATSHRACHESIGMAR1CYP3A4 | |
| SCHEMBL9355683 | 0.78 | CA12 (0.44) | LMNATSHRACHESIGMAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |