Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063156 | 0.98 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2TDP1SIGMAR1GAA | |
| SCHEMBL8059112 | 0.84 | SIGMAR1 (0.50) | ALDH1A1SMN1; SMN2SIGMAR1GAAPOLB | |
| SCHEMBL8059039 | 0.82 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2SIGMAR1MEN1KMT2A | |
| SCHEMBL2928831 | 0.81 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2TDP1GAAL3MBTL1 | |
| SCHEMBL25570287 | 0.81 | HTT (0.55) | ALDH1A1SMN1; SMN2TDP1SIGMAR1POLB | |
| SCHEMBL2924557 | 0.79 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2TDP1GAAL3MBTL1 | |
| SCHEMBL19958938 | 0.77 | SIGMAR1 (0.43) | ALDH1A1SMN1; SMN2TDP1SIGMAR1 | |
| SCHEMBL24926262 | 0.77 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2TDP1SIGMAR1GAA | |
| SCHEMBL12454178 | 0.77 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2TDP1SIGMAR1GAA | |
| SCHEMBL24926282 | 0.77 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2TDP1SIGMAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071735-A1 | Compounds for Increasing Lipid Synthesis and Storage | WASE, NISHIKANT | 2020-03-05 | — | — | US | disclosed |
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | NUTECH VENTURES (US) | 2019-07-16 | — | — | US | disclosed |
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | INVITROGEN CORPORATION | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160312253-A1 | Compounds for Increasing Lipid Synthesis and Storage | FASN, LIPC, SREBF2 | ALDH1A1 1121/4885SMN1; SMN2 4517/4885TDP1 4102/4885 |
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | FASN, LIPC, SREBF2 | ALDH1A1 1121/4885SMN1; SMN2 4517/4885TDP1 4102/4885 |
| US-20200071735-A1 | Compounds for Increasing Lipid Synthesis and Storage | FASN, LIPC, SREBF2 | ALDH1A1 1121/4885SMN1; SMN2 4517/4885TDP1 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.