Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178778 | 0.92 | ACHE (0.36) | ALDH1A1LMNAKDM4ENPSR1ACHE | |
| SCHEMBL18178658 | 0.91 | SLC22A12 (0.37) | ALDH1A1LMNAAKR1C3SMN1; SMN2KDM4E | |
| SCHEMBL18178703 | 0.91 | ALDH1A1 (0.36) | ALDH1A1AKR1C3ACHEMRGPRX4MAPT | |
| SCHEMBL18182469 | 0.90 | MRGPRX4 (0.36) | ALDH1A1MRGPRX4KMT2AATML3MBTL1 | |
| SCHEMBL18178299 | 0.90 | LMNA (0.38) | ALDH1A1LMNAAKR1C3SMN1; SMN2KDM4E | |
| SCHEMBL18178677 | 0.90 | MRGPRX4 (0.36) | ALDH1A1LMNASMN1; SMN2ACHENPC1 | |
| SCHEMBL18178699 | 0.89 | ALDH1A1 (0.39) | ALDH1A1RAB9AMAPTGAAKMT2A | |
| SCHEMBL18178674 | 0.89 | MRGPRX4 (0.39) | ALDH1A1LMNAAKR1C3SMN1; SMN2KDM4E | |
| SCHEMBL18178597 | 0.89 | MRGPRX4 (0.35) | ALDH1A1LMNAKDM4ENPSR1ACHE | |
| SCHEMBL18178649 | 0.88 | ACHE (0.36) | ALDH1A1LMNAAKR1C3SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | ALDH1A1 3176/4885LMNA 4171/4885AKR1C3 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.