SCHEMBL1817953

SCHEMBL1817953

Fc1cccc(F)c1S.[Zn]

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.39
CES1 P23141 4/20 0.39
ACHE P22303 1/20 0.36
NFE2L2 Q16236 3/20 0.35
BCHE P06276 1/20 0.35
ALB P02768 1/20 0.32
ERN1 O75460 1/20 0.32
TAAR1 Q96RJ0 2/20 0.31
PKM P14618 1/20 0.31
PKLR P30613 1/20 0.31
TTR P02766 1/20 0.30
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457725 0.97
SCHEMBL1815421 0.93 CES2 (0.39) CES2CES1ACHENFE2L2BCHE
SCHEMBL1967992 0.81
SCHEMBL27543087 0.81 ALDH1A1 (0.38) CES2CES1TAAR1
SCHEMBL1729975 0.81 ALDH1A1 (0.38) CES2CES1TAAR1
SCHEMBL16266220 0.79 TRPV4 (0.40) CES2CES1
SCHEMBL9191241 0.77
SCHEMBL13429846 0.77
SCHEMBL15352112 0.77
SCHEMBL5619974 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592526-B2 Golf ball SRI SPORTS LIMITED (JP) 2013-11-26 US claimed
US-20110105244-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-05-05 US claimed
US-8592526-B2 Golf ball SRI SPORTS LIMITED (JP) 2013-11-26 US disclosed
US-20110105244-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-05-05 US disclosed