Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180501 | 0.87 | FYN (0.46) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL18180502 | 0.80 | CYP11B1 (0.54) | CYP17A1PIK3CA | |
| SCHEMBL20015622 | 0.73 | TTR (0.41) | KDM4ECYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL16113607 | 0.71 | CTSA (0.43) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL30989366 | 0.69 | TRPA1 (0.34) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL20864258 | 0.69 | SLC13A5 (0.54) | CYP3A4 | |
| SCHEMBL424070 | 0.69 | FGFR2 (0.39) | MEN1KMT2AKDM4EGRM2NPC1 | |
| SCHEMBL19932623 | 0.68 | MKNK1 (0.53) | CYP1A2USP1 | |
| SCHEMBL28097912 | 0.68 | MAPT (0.41) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| SCHEMBL19330231 | 0.67 | MEN1 (0.39) | MEN1KMT2AKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
| EP-3287453-A1 | IMIDAZOLE COMPOUND | Medshine Discovery Inc. (CN) | 2018-02-28 | — | — | EP | disclosed |
| EP-3287453-A1 | IMIDAZOLE COMPOUND | Medshine Discovery Inc. (CN) | 2018-02-28 | — | — | EP | disclosed |
| CN-106065012-A | Glyoxaline compound | 广东众生药业股份有限公司 | 2016-11-02 | — | — | CN | disclosed |
| WO-2016169514-A1 | IMIDAZOLE COMPOUND | 广东众生药业股份有限公司 | 2016-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MAPT, SLC10A2, SLC5A11 | MEN1 574/4885KMT2A 2814/4885KDM4E 3548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.